It means you are trying to create a food with incorrect information.

Protein has 4 calories per gram, Carbs 4 calories, and Fat 9 calories.

The app is telling you, based on the grams of protein, carbs, and fat you have entered the food should have 181 calories. However, you put 410 calories. Either your macros are wrong, your calories are wrong, or both.

Thank you so much!